Kallikrein 1 antibody (Internal Region)

Catalog No. ABIN7218418

The Rabbit Polyclonal anti-Kallikrein 1 antibody (ABIN7218418) specifically detects Kallikrein 1 in WB and IHC. The antibody is reactive with Human and Mouse samples.

Quick Overview for Kallikrein 1 antibody (Internal Region) (ABIN7218418)

Target: Kallikrein 1 (KLK1)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Kallikrein 1 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-KLK1 Polyclonal Antibody

Specificity: KLK1 Polyclonal Antibody detects endogenous levels of KLK1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human KLK1

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Kallikrein 1

Target: Kallikrein 1 (KLK1)

Alternative Name: KLK1

Background: KLK1, Kallikrein-1, Kidney/pancreas/salivary gland kallikrein, Tissue kallikreinKallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK1 is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.

Molecular Weight: 29kD

Gene ID: 3816

UniProt: P06870

Pathways: Complement System