Kallikrein 11 antibody (Cleaved-Ile54)

Catalog No. ABIN7212478

This Rabbit Polyclonal antibody specifically detects Kallikrein 11 in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Kallikrein 11 antibody (Cleaved-Ile54) (ABIN7212478)

Target: Kallikrein 11 (KLK11)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 11 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Kallikrein 11 Antibody

Binding Specificity: AA 10-90, Cleaved-Ile54

Purpose: Rabbit Anti-Cleaved-KLK11 (I54) Polyclonal Antibody

Specificity: Cleaved-KLK11 (I54) Polyclonal Antibody detects endogenous levels of fragment of activated KLK11 protein resulting from cleavage adjacent to I54.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human KLK11 at AA range: 10-90

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Kallikrein 11

Target: Kallikrein 11 (KLK11)

Alternative Name: KLK11

Background: KLK11, PRSS20, TLSP, Kallikrein-11, hK11, Hippostasin, Serine protease 20, Trypsin-like proteaseKallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK11 is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of KLK11 results in multiple transcript variants encoding distinct isoforms which are differentially expressed.

Molecular Weight: 25kD

Gene ID: 11012

UniProt: Q9UBX7

Pathways: Complement System