Kallikrein 12 antibody

Catalog No. ABIN7229306

The Rabbit Polyclonal anti-Kallikrein 12 antibody is suitable to detect Kallikrein 12 in samples from Human and Rat. It has been validated for WB and ELISA.

Quick Overview for Kallikrein 12 antibody (ABIN7229306)

Target: Kallikrein 12 (KLK12) (Kallikrein-Related Peptidase 12 (KLK12))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Kallikrein 12 Antibody

Purpose: Rabbit Anti-KLK12 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of KLK12 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human KLK12 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Kallikrein 12

Target: Kallikrein 12 (KLK12) (Kallikrein-Related Peptidase 12 (KLK12))

Alternative Name: KLK12

Background: Kallikrein-12, Kallikrein-like protein 5, KLK-L5Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK12 is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of KLK12 results in three transcript variants encoding different isoforms. KLK12 (Kallikrein Related Peptidase 12) is a Protein Coding gene. Among its related pathways are Keratinization and Collagen chain trimerization.

Molecular Weight: 27kD

Gene ID: 43849

UniProt: Q9UKR0

Pathways: Complement System