Cytokeratin 5 antibody (AA 510-590)
Quick Overview for Cytokeratin 5 antibody (AA 510-590) (ABIN7214492)
Target
See all Cytokeratin 5 (KRT5) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 510-590
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Purpose
- Cytokeratin 5 Polyclonal Antibody
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Specificity
- Cytokeratin 5 Polyclonal Antibody detects endogenous levels of Cytokeratin 5 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the C-terminal region of human Cytokeratin 5 at AA range: 510-590
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))
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Alternative Name
- Cytokeratin 5
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Background
- Rabbit Anti-Cytokeratin 5 Polyclonal Antibody,KRT5, Keratin, type II cytoskeletal 5, 58 kDa cytokeratin, Cytokeratin-5, CK-5, Keratin-5, K5, Type-II keratin Kb5,Keratin 5 encoded by KRT5 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.,Keratin type II cytoskeletal 5
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Molecular Weight
- observerd band 62kDa
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Gene ID
- 3852
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UniProt
- P13647
Target
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