pan Keratin antibody

Catalog No. ABIN7218192

The Rabbit Polyclonal anti-pan Keratin antibody (ABIN7218192) specifically detects pan Keratin in IF, IHC, WB and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for pan Keratin antibody (ABIN7218192)

Target: pan Keratin (panKRT)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This pan Keratin antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Product Details anti-pan Keratin Antibody

Purpose: Rabbit Anti-Keratin-pan Polyclonal Antibody

Specificity: Keratin-pan Polyclonal Antibody detects endogenous levels of Keratin-pan protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Keratin-pan around the non-acetylation site of K185

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for pan Keratin

Target: pan Keratin (panKRT)

Alternative Name: Keratin-pan

Background: KRT2, KRT76, KRT3, KRT5, KRT6A, KRT6B, KRT6C, KRT71, KRT72, KRT73, KRT74, KRT75, KRT79, KRT8, KRT84, Keratin, type II cytoskeletal 2 epidermal, Keratin, type II cytoskeletal 2 oral, Keratin, type II cytoskeletal 3, Keratin, type II cytoskeletal 5, Keratin, type II cytoskeletal 6A, Keratin, type II cytoskeletal 6B, Keratin, type II cytoskeletal 6C, Keratin, type II cytoskeletal 71, Keratin, type II cytoskeletal 72, Keratin, type II cytoskeletal 73, Keratin, type II cytoskeletal 74,Keratin 2 encoded by KRT2 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Molecular Weight: 65kD

Gene ID: 3849

UniProt: P35908