Tspan-8 antibody (AA 101-200)

Catalog No. ABIN716246

The Rabbit Polyclonal anti-Tspan-8 antibody has been validated for WB, ELISA, ICC, IF (cc), IF (p), IHC (fro) and IHC (p). It is suitable to detect Tspan-8 in samples from Human. There is 1 publication available.

Quick Overview for Tspan-8 antibody (AA 101-200) (ABIN716246)

Target: Tspan-8 (TSPAN8) (Tetraspanin 8 (TSPAN8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tspan-8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Tspan-8 Antibody

Binding Specificity: AA 101-200

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TM4SF3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Tspan-8 antibody (ABIN716246)

Bhansali, Zhou, Shemshedini: "TM4SF3 and AR: A Nuclear Complex that Stabilizes Both Proteins." in: Molecular endocrinology (Baltimore, Md.), Vol. 30, Issue 1, pp. 13-25, (2016) (PubMed).

Target Details for Tspan-8

Target: Tspan-8 (TSPAN8) (Tetraspanin 8 (TSPAN8))

Alternative Name: Tm4sf3

Background:

Synonyms: CO-029, TM4SF3, Tetraspanin-8, Tspan-8, Transmembrane 4 superfamily member 3, Tumor-associated antigen CO-029, TSPAN8

Background: TM4SF3 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TM4SF3 is known to complex with integrins. Its gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for TM4SF3 gene.

Gene ID: 7103

UniProt: P19075