Tspan-8 antibody (AA 70-150)

Catalog No. ABIN7217278

The Rabbit Polyclonal anti-Tspan-8 antibody is suitable to detect Tspan-8 in samples from Human and Mouse. It has been validated for WB, ELISA, IF and IHC.

Quick Overview for Tspan-8 antibody (AA 70-150) (ABIN7217278)

Target: Tspan-8 (TSPAN8) (Tetraspanin 8 (TSPAN8))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tspan-8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-Tspan-8 Antibody

Binding Specificity: AA 70-150

Purpose: Rabbit Anti-Tetraspanin-8 Polyclonal Antibody

Specificity: Tetraspanin-8 Polyclonal Antibody detects endogenous levels of Tetraspanin-8 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Tetraspanin-8 at AA range: 70-150

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Tspan-8

Target: Tspan-8 (TSPAN8) (Tetraspanin 8 (TSPAN8))

Alternative Name: Tetraspanin-8

Background: TSPAN8, TM4SF3, Tetraspanin-8, Tspan-8, Transmembrane 4 superfamily member 3, Tumor-associated antigen CO-029Tetraspanin-8 encoded by TSPAN8 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. Tetraspanin-8 mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene.

Molecular Weight: 26kD

Gene ID: 7103

UniProt: P19075