Krs-1/2 antibody
Quick Overview for Krs-1/2 antibody (ABIN7224530)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Purpose
- Krs-1/2 Polyclonal Antibody
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Specificity
- Krs-1/2 Polyclonal Antibody detects endogenous levels of Krs-1/2 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from human Krs-1/2 around the non-phosphorylation site of T183
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Krs-1/2
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Background
- Rabbit Anti-Krs-1/2 Polyclonal Antibody,STK3, KRS1, MST2, Serine/threonine-protein kinase 3, Mammalian STE20-like protein kinase 2, MST-2, STE20-like kinase MST2, Serine/threonine-protein kinase Krs-1, STK4, KRS2, MST1, Serine/threonine-protein kinase 4, Mammalian STE20-like prot,STK3 (serine/threonine kinase 3) encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for STK3.,serine threonine-protein kinase 3
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Molecular Weight
- observerd band 56kDa
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Gene ID
- 6788, 6789
Target
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