Laminin antibody (AA 1980-2060)

Catalog No. ABIN7222140

This anti-Laminin antibody is a Rabbit Polyclonal antibody detecting Laminin in ELISA, IF and IHC (p). Suitable for Human and Mouse.

Quick Overview for Laminin antibody (AA 1980-2060) (ABIN7222140)

Target: Laminin (LAMA2) (Laminin, alpha 2 (LAMA2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Laminin antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Laminin Antibody

Binding Specificity: AA 1980-2060

Purpose: Laminin α-2 Polyclonal Antibody

Specificity: Laminin α-2 Polyclonal Antibody detects endogenous levels of Laminin α-2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Laminin alpha-2 at AA range: 1980-2060

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Laminin

Target: Laminin (LAMA2) (Laminin, alpha 2 (LAMA2))

Alternative Name: Laminin alpha-2

Background: Rabbit Anti-Laminin α-2 Polyclonal Antibody,LAMA2, LAMM, Laminin subunit alpha-2, Laminin M chain, Laminin-12 subunit alpha, Laminin-2 subunit alpha, Laminin-4 subunit alpha, Merosin heavy chain,Laminin, an extracellular protein, is a major component of the basement membrane. It is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. LAMA2 encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene.,Laminin subunit alpha-2

Gene ID: 3908

UniProt: P24043