LMTK2 antibody (AA 620-700)

Catalog No. ABIN7220554

This Rabbit Polyclonal antibody specifically detects LMTK2 in WB, ELISA, IF and IHC (p). It exhibits reactivity toward Human.

Quick Overview for LMTK2 antibody (AA 620-700) (ABIN7220554)

Target: LMTK2 (Lemur tyrosine Kinase 2 (LMTK2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LMTK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-LMTK2 Antibody

Binding Specificity: AA 620-700

Purpose: KPI-2 Polyclonal Antibody

Specificity: KPI-2 Polyclonal Antibody detects endogenous levels of KPI-2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human KPI-2 at AA range: 620-700

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for LMTK2

Target: LMTK2 (Lemur tyrosine Kinase 2 (LMTK2))

Alternative Name: KPI-2

Background: Rabbit Anti-KPI-2 Polyclonal Antibody,LMTK2, AATYK2, BREK, KIAA1079, KPI2, LMR2, Serine/threonine-protein kinase LMTK2, Apoptosis-associated tyrosine kinase 2, Brain-enriched kinase, hBREK, CDK5/p35-regulated kinase, CPRK, Kinase/phosphatase/inhibitor 2, Lemur tyrosine kinase 2,The lemur tyrosine kinase 2 encoded by LMTK2 belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. This protein interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. This protein involves in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggested an essential role of this protein in spermatogenesis.,serine threonine-protein kinase LMTK2

Molecular Weight: observerd band 164kDa

Gene ID: 22853

UniProt: Q8IWU2

Pathways: RTK Signaling, Neurotrophin Signaling Pathway