LMTK3 antibody (AA 1220-1300)

Catalog No. ABIN7219336

The Rabbit Polyclonal anti-LMTK3 antibody is suitable to detect LMTK3 in samples from Human and Mouse. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for LMTK3 antibody (AA 1220-1300) (ABIN7219336)

Target: LMTK3 (Lemur Tyrosine Kinase 3 (LMTK3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LMTK3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-LMTK3 Antibody

Binding Specificity: AA 1220-1300

Purpose: Rabbit Anti-LMTK3 Polyclonal Antibody

Specificity: LMTK3 Polyclonal Antibody detects endogenous levels of LMTK3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human LMTK3 at AA range: 1220-1300

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for LMTK3

Target: LMTK3 (Lemur Tyrosine Kinase 3 (LMTK3))

Alternative Name: LMTK3

Background: LMTK3, KIAA1883, TYKLM3, Serine/threonine-protein kinase LMTK3, Lemur tyrosine kinase 3LMTK3 (Lemur Tyrosine Kinase 3) is a Protein Coding gene. Among its related pathways are ERK Signaling and Akt Signaling. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is AATK. rotein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (PubMed: 21602804). Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons (By similarity).

Molecular Weight: 153kD

Gene ID: 114783

UniProt: Q96Q04