LECT1 antibody (AA 150-230)

Catalog No. ABIN7229384

The Rabbit Polyclonal anti-LECT1 antibody is suitable to detect LECT1 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for LECT1 antibody (AA 150-230) (ABIN7229384)

Target: LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LECT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-LECT1 Antibody

Binding Specificity: AA 150-230

Purpose: Rabbit Anti-LECT1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of LECT1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human LECT1 protein at AA range: 150-230

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for LECT1

Target: LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))

Alternative Name: LECT1

Background: Leukocyte cell-derived chemotaxin 1, ChondromodulinCNMD encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. CNMD is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 36kD

Gene ID: 11061

UniProt: O75829