Leukotriene B4 Receptor/BLT antibody

Catalog No. ABIN7229470

The Rabbit Polyclonal anti-Leukotriene B4 Receptor/BLT antibody is suitable to detect Leukotriene B4 Receptor/BLT in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for Leukotriene B4 Receptor/BLT antibody (ABIN7229470)

Target: Leukotriene B4 Receptor/BLT (LTB4R) (Leukotriene B4 Receptor (LTB4R))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Leukotriene B4 Receptor/BLT antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Leukotriene B4 Receptor/BLT Antibody

Purpose: Rabbit Anti-LT4R1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of LT4R1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human LT4R1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Leukotriene B4 Receptor/BLT

Target: Leukotriene B4 Receptor/BLT (LTB4R) (Leukotriene B4 Receptor (LTB4R))

Alternative Name: LT4R1

Background: Leukotriene B4 receptor 1, LTB4-R 1, LTB4-R1, Chemoattractant receptor-like 1, G-protein coupled receptor 16, P2Y purinoceptor 7, P2Y7LTB4R (Leukotriene B4 Receptor) is a Protein Coding gene. Diseases associated with LTB4R include Image Syndrome. Among its related pathways are Nucleotide-like (purinergic) receptors and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and leukotriene receptor activity. An important paralog of this gene is LTB4R2. Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.

Molecular Weight: 38kD

Gene ID: 1241

UniProt: Q15722