LSM1 antibody (AA 50-130)

Catalog No. ABIN7229462

The Rabbit Polyclonal anti-LSM1 antibody is suitable to detect LSM1 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for LSM1 antibody (AA 50-130) (ABIN7229462)

Target: LSM1 (LSM1 Homolog, U6 Small Nuclear RNA Associated (LSM1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LSM1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-LSM1 Antibody

Binding Specificity: AA 50-130

Purpose: Rabbit Anti-LSM1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of LSM1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human LSM1 protein at AA range: 50-130

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for LSM1

Target: LSM1 (LSM1 Homolog, U6 Small Nuclear RNA Associated (LSM1))

Alternative Name: LSM1

Background: U6 snRNA-associated Sm-like protein LSm1, Cancer-associated Sm-like, Small nuclear ribonuclear CaSmLSM1 encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Increased expression of LSM1 may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced transcript variants have been observed for LSM1, and a pseudogene of LSM1 is located on the short arm of chromosome 9.

Molecular Weight: 14kD

Gene ID: 27257

UniProt: O15116