LUM antibody (AA 30-110)

Catalog No. ABIN7229480

This Rabbit Polyclonal antibody specifically detects LUM in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for LUM antibody (AA 30-110) (ABIN7229480)

Target: LUM (Lumican (LUM))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LUM antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-LUM Antibody

Binding Specificity: AA 30-110

Purpose: Rabbit Anti-LUM Polyclonal Antibody

Specificity: The antibody detects endogenous levels of LUM protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human LUM protein at AA range: 30-110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for LUM

Target: LUM (Lumican (LUM))

Alternative Name: LUM

Background: Keratan sulfate proteoglycan lumican, KSPG lumicanLUM encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair.

Molecular Weight: 37kD

Gene ID: 4060

UniProt: P51884

Pathways: Glycosaminoglycan Metabolic Process