LTB antibody (AA 41-90)

Catalog No. ABIN7229478

This Rabbit Polyclonal antibody specifically detects LTB in WB, ELISA, IHC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for LTB antibody (AA 41-90) (ABIN7229478)

Target: LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LTB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-LTB Antibody

Binding Specificity: AA 41-90

Purpose: Rabbit Anti-LT-β Polyclonal Antibody

Specificity: The antibody detects endogenous levels of LT-β

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human LT-beta protein at AA range: 41-90

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,WB 1:500-2000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for LTB

Target: LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))

Alternative Name: LT-beta

Background: Lymphotoxin-beta, LT-beta, Tumor necrosis factor C, TNF-C, Tumor necrosis factor ligand superfamily member 3Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants.

Gene ID: 4050

UniProt: Q06643

Pathways: NF-kappaB Signaling