LTA antibody (Internal Region)

Catalog No. ABIN7217348

The Rabbit Polyclonal anti-LTA antibody (ABIN7217348) specifically detects LTA in WB and ELISA. The antibody is reactive with Human, Rat, Mouse and Monkey samples.

Quick Overview for LTA antibody (Internal Region) (ABIN7217348)

Target: LTA (Lymphotoxin-alpha (LTA))

Reactivity: Human, Rat, Mouse, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LTA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-LTA Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-TNF-β Polyclonal Antibody

Specificity: TNF-β Polyclonal Antibody detects endogenous levels of TNF-β protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human TNF-beta

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for LTA

Target: LTA (Lymphotoxin-alpha (LTA))

Alternative Name: TNF-beta

Target Type: Chemical

Background: LTA, TNFB, TNFSF1, Lymphotoxin-alpha, LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1The lymphotoxin-alpha, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. Lymphotoxin-alpha is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene.

Molecular Weight: 22kD

Gene ID: 4049

UniProt: P01374

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process