CHRM5 antibody (AA 260-340)

Catalog No. ABIN7219312

This Rabbit Polyclonal antibody specifically detects CHRM5 in WB, ELISA and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CHRM5 antibody (AA 260-340) (ABIN7219312)

Target: CHRM5 (Cholinergic Receptor, Muscarinic 5 (CHRM5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRM5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-CHRM5 Antibody

Binding Specificity: AA 260-340

Purpose: Rabbit Anti-mAChR M5 Polyclonal Antibody

Specificity: MAChR M5 Polyclonal Antibody detects endogenous levels of mAChR M5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human mAChR M5 at AA range: 260-340

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CHRM5

Target: CHRM5 (Cholinergic Receptor, Muscarinic 5 (CHRM5))

Alternative Name: mAChR M5

Background: CHRM5, Muscarinic acetylcholine receptor M5The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown, however, stimulation of this receptor is known to increase cyclic AMP levels.

Molecular Weight: 60kD

Gene ID: 1133

UniProt: P08912

Pathways: Synaptic Membrane