MDGA1 antibody

Catalog No. ABIN7229612

The Rabbit Polyclonal anti-MDGA1 antibody is suitable to detect MDGA1 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for MDGA1 antibody (ABIN7229612)

Target: MDGA1 (MAM Domain Containing Glycosylphosphatidylinositol Anchor 1 (MDGA1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MDGA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MDGA1 Antibody

Purpose: Rabbit Anti-MDGA1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MDGA1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MDGA1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MDGA1

Target: MDGA1 (MAM Domain Containing Glycosylphosphatidylinositol Anchor 1 (MDGA1))

Alternative Name: MDGA1

Background: MAM domain-containing glycosylphosphatidylinositol anchor protein 1, GPI and MAM protein, GPIM, Glycosylphosphatidylinositol-MAM, MAM domain-containing protein 3MDGA1 encodes a glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein that is expressed predominantly in the developing nervous system. In addition to possessing several cell adhesion molecule-like domains, the mature protein has six Ig-like domains, a single fibronectin type III domain, a MAM domain and a C-terminal GPI-anchoring site. Studies in other mammals suggest MAM Domain Containing Glycosylphosphatidylinositol Anchor 1 plays a role in cell adhesion, migration, and axon guidance and, in the developing brain, neuronal migration. In humans, this gene is associated with bipolar disorder and schizophrenia.

Molecular Weight: 105kD

Gene ID: 266727

UniProt: Q8NFP4