MARK4 antibody (AA 430-510)

Catalog No. ABIN7223828

This Rabbit Polyclonal antibody specifically detects MARK4 in ELISA and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for MARK4 antibody (AA 430-510) (ABIN7223828)

Target: MARK4 (MAP/microtubule Affinity-Regulating Kinase 4 (MARK4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARK4 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-MARK4 Antibody

Binding Specificity: AA 430-510

Purpose: MARK4 Polyclonal Antibody

Specificity: MARK4 Polyclonal Antibody detects endogenous levels of MARK4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human MARK4 at AA range: 430-510

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF (1:200-1:1000), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for MARK4

Target: MARK4 (MAP/microtubule Affinity-Regulating Kinase 4 (MARK4))

Alternative Name: MARK4

Background: Rabbit Anti-MARK4 Polyclonal Antibody,MARK4, KIAA1860, MARKL1, MAP/microtubule affinity-regulating kinase 4, MAP/microtubule affinity-regulating kinase-like 1,MARK4 (microtubule affinity regulating kinase 4) encodes a member of the microtubule affinity-regulating kinase family. These protein kinases phosphorylate microtubule-associated proteins and regulate the transition between stable and dynamic microtubules. The encoded protein is associated with the centrosome throughout mitosis and may be involved in cell cycle control. Expression of MARK4 is a potential marker for cancer, and the encoded protein may also play a role in Alzheimer's disease. Pseudogenes of MARK4 are located on both the short and long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for MARK4.,MAP

Molecular Weight: observerd band 83kDa

Gene ID: 57787

UniProt: Q96L34