MRGPRD antibody

Catalog No. ABIN7229754

This anti-MRGPRD antibody is a Rabbit Polyclonal antibody detecting MRGPRD in WB and ELISA. Suitable for Human.

Quick Overview for MRGPRD antibody (ABIN7229754)

Target: MRGPRD (MAS-Related GPR, Member D (MRGPRD))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRGPRD antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MRGPRD Antibody

Purpose: MRGRD Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MRGRD protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human MRGRD protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for MRGPRD

Target: MRGPRD (MAS-Related GPR, Member D (MRGPRD))

Alternative Name: MRGRD

Background: Rabbit Anti-MRGRD Polyclonal Antibody,Mas-related G-protein coupled receptor member D, Beta-alanine receptor, G-protein coupled receptor TGR7,MRGPRD (MAS Related GPR Family Member D) is a Protein Coding gene. Among its related pathways are ACE Inhibitor Pathway, Pharmacodynamics. GO annotations related to this gene include G-protein coupled receptor activity. An important paralog of this gene is MRGPRX4. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).,MRGRD

Molecular Weight: observerd band 35kDa

Gene ID: 116512

UniProt: Q8TDS7