MXI1 antibody

Catalog No. ABIN7229804

The Rabbit Polyclonal anti-MXI1 antibody has been validated for WB and ELISA. It is suitable to detect MXI1 in samples from Human, Mouse and Rat.

Quick Overview for MXI1 antibody (ABIN7229804)

Target: MXI1 (MAX Interactor 1 (MXI1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MXI1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MXI1 Antibody

Purpose: MXI1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MXI1 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human MXI1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for MXI1

Target: MXI1 (MAX Interactor 1 (MXI1))

Alternative Name: MXI1

Background: Rabbit Anti-MXI1 Polyclonal Antibody,Max-interacting protein 1, Max interactor 1, Class C basic helix-loop-helix protein 11, bHLHc11,Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. MAX Interactor 1, Dimerization Protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.,MXI1

Molecular Weight: observerd band 25kDa

Gene ID: 4601

UniProt: P50539

Pathways: Maintenance of Protein Location