MCF2 antibody

Catalog No. ABIN7229594

The Rabbit Polyclonal anti-MCF2 antibody is suitable to detect MCF2 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for MCF2 antibody (ABIN7229594)

Target: MCF2 (MCF.2 Cell Line Derived Transforming Sequence (MCF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MCF2 Antibody

Purpose: Rabbit Anti-MCF2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MCF2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MCF2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MCF2

Target: MCF2 (MCF.2 Cell Line Derived Transforming Sequence (MCF2))

Alternative Name: MCF2

Background: Proto-oncogene DBL, Proto-oncogene MCF-2The oncogenic protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that exerts control over some members of the Rho family of small GTPases. Several transcript variants encoding different isoforms have been found for this gene. These isoforms exhibit different expression patterns and varying levels of GEF activity. MCF2 (MCF. Cell Line Derived Transforming Sequence) is a Protein Coding gene. Diseases associated with MCF2 include Xeroderma Pigmentosum, Group B and Aarskog-Scott Syndrome. Among its related pathways are p75 NTR receptor-mediated signalling and RET signaling.

Molecular Weight: 101kD

Gene ID: 4168

UniProt: P10911