MCF2L antibody

Catalog No. ABIN7229596

This anti-MCF2L antibody is a Rabbit Polyclonal antibody detecting MCF2L in WB and ELISA. Suitable for Human.

Quick Overview for MCF2L antibody (ABIN7229596)

Target: MCF2L (MCF.2 Cell Line Derived Transforming Sequence-Like (MCF2L))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCF2L antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MCF2L Antibody

Purpose: MCF2L Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MCF2L protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human MCF2L protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for MCF2L

Target: MCF2L (MCF.2 Cell Line Derived Transforming Sequence-Like (MCF2L))

Alternative Name: MCF2L

Background: Rabbit Anti-MCF2L Polyclonal Antibody,Guanine nucleotide exchange factor DBS, DBL's big sister, MCF2-transforming sequence-like protein,MCF2L encodes a guanine nucleotide exchange factor that interacts specifically with the GTP-bound Rac1 and plays a role in the Rho/Rac signaling pathways. A variant in this gene was associated with osteoarthritis. Alternative splicing results in multiple transcript variants. MCF2L (MCF. Cell Line Derived Transforming Sequence Like) is a Protein Coding gene. Diseases associated with MCF2L include Atypical Autism and Osteoarthritis. Among its related pathways are p75 NTR receptor-mediated signalling and Phospholipase-C Pathway.,MCF2L

Molecular Weight: observerd band 125kDa

Gene ID: 23263

UniProt: O15068

Pathways: Neurotrophin Signaling Pathway, Metabolism of Steroid Hormones and Vitamin D, Thyroid Hormone Synthesis