MCHR1 antibody

Catalog No. ABIN7229598

The Rabbit Polyclonal anti-MCHR1 antibody is suitable to detect MCHR1 in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.

Quick Overview for MCHR1 antibody (ABIN7229598)

Target: MCHR1 (Melanin-Concentrating Hormone Receptor 1 (MCHR1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCHR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MCHR1 Antibody

Purpose: Rabbit Anti-MCHR1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MCHR1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MCHR1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MCHR1

Target: MCHR1 (Melanin-Concentrating Hormone Receptor 1 (MCHR1))

Alternative Name: MCHR1

Background: Melanin-concentrating hormone receptor 1, MCH receptor 1, MCH-R1, MCHR-1, G-protein coupled receptor 24, MCH-1R, MCH1R, MCHR, SLC-1, Somatostatin receptor-like proteinThe protein encoded by MCHR1, a member of the G protein-coupled receptor family 1, is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, this protein does not seem to bind somatostatin.

Molecular Weight: 46kD

Gene ID: 2847

UniProt: Q99705

Pathways: Feeding Behaviour