MAGEA2B antibody (AA 50-130)

Catalog No. ABIN7229510

The Rabbit Polyclonal anti-MAGEA2B antibody (ABIN7229510) specifically detects MAGEA2B in ELISA and WB. The antibody is reactive with Human samples.

Quick Overview for MAGEA2B antibody (AA 50-130) (ABIN7229510)

Target: MAGEA2B (Melanoma Antigen Family A, 2B (MAGEA2B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEA2B antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-MAGEA2B Antibody

Binding Specificity: AA 50-130

Purpose: Rabbit Anti-MAGA2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MAGA2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MAGA2 protein at AA range: 50-130

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MAGEA2B

Target: MAGEA2B (Melanoma Antigen Family A, 2B (MAGEA2B))

Alternative Name: MAGA2

Background: Melanoma-associated antigen 2, Cancer/testis antigen 1.2, CT1.2, MAGE-2 antigenMAGEA2 (MAGE Family Member A2) is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of MAGEA2 family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. MAGEA2 has two identical copies at different loci. Alternatively spliced transcript variants encoding the same protein have been identified for MAGEA2. MAGEA2 is a Protein Coding gene. Diseases associated with MAGEA2 include Melanoma and Dyskeratosis Congenita.

Molecular Weight: 34kD

Gene ID: 266740

UniProt: P43356