MAGEA5 antibody (AA 40-120)

Catalog No. ABIN7222316

The Rabbit Polyclonal anti-MAGEA5 antibody (ABIN7222316) specifically detects MAGEA5 in ELISA and WB. The antibody is reactive with Human samples.

Quick Overview for MAGEA5 antibody (AA 40-120) (ABIN7222316)

Target: MAGEA5 (Melanoma Antigen Family A, 5 (MAGEA5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEA5 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-MAGEA5 Antibody

Binding Specificity: AA 40-120

Purpose: Rabbit Anti-MAGE-A5 Polyclonal Antibody

Specificity: MAGE-A5 Polyclonal Antibody detects endogenous levels of MAGE-A5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human MAGE-A5 at AA range: 40-120

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MAGEA5

Target: MAGEA5 (Melanoma Antigen Family A, 5 (MAGEA5))

Alternative Name: MAGE-A5

Background: MAGEA5, MAGE5, Melanoma-associated antigen 5, Cancer/testis antigen 1.5, CT1.5, MAGE-5 antigenMAGEA5 is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This MAGEA gene encodes a protein that is C-terminally truncated compared to other family members, and this gene can be alternatively interpreted to be a pseudogene. The protein is represented in this Gene record in accordance with the assumed protein-coding status defined in the literature. Read-through transcription exists between this gene and the upstream melanoma antigen family A, 10 (MAGEA10) gene.

Molecular Weight: 36kD

Gene ID: 4104

UniProt: P43359