MAGEB1 antibody (AA 70-150)

Catalog No. ABIN7229524

This Rabbit Polyclonal antibody specifically detects MAGEB1 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for MAGEB1 antibody (AA 70-150) (ABIN7229524)

Target: MAGEB1 (Melanoma Antigen Family B, 1 (MAGEB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MAGEB1 Antibody

Binding Specificity: AA 70-150

Purpose: Rabbit Anti-MAGB1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MAGB1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MAGB1 protein at AA range: 70-150

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MAGEB1

Target: MAGEB1 (Melanoma Antigen Family B, 1 (MAGEB1))

Alternative Name: MAGB1

Background: Melanoma-associated antigen B1, Cancer/testis antigen 3.1, CT3.1, DSS-AHC critical interval MAGE superfamily 10, DAM10, MAGE-B1 antigen, MAGE-XP antigenMAGEB1 is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68 % sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. MAGEB1 is localized in the DSS (dosage-sensitive sex reversal) critical region, and expressed in testis and in a significant fraction of tumors of various histological types. MAGEB1 and other MAGEB members are clustered on chromosome Xp22-p21. Multiple alternatively spliced transcript variants encoding the same protein have been found for MAGEB1, however, the full length nature of some variants has not been defined. MAGEB4 is expressed in testis.

Molecular Weight: 38kD

Gene ID: 4112

UniProt: P43366