MAGEB2 antibody (AA 30-110)

Catalog No. ABIN7229526

This Rabbit Polyclonal antibody specifically detects MAGEB2 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for MAGEB2 antibody (AA 30-110) (ABIN7229526)

Target: MAGEB2 (Melanoma Antigen Family B, 2 (MAGEB2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEB2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MAGEB2 Antibody

Binding Specificity: AA 30-110

Purpose: Rabbit Anti-MAGB2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MAGB2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MAGB2 protein at AA range: 30-110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MAGEB2

Target: MAGEB2 (Melanoma Antigen Family B, 2 (MAGEB2))

Alternative Name: MAGB2

Background: Melanoma-associated antigen B2, Cancer/testis antigen 3.2, CT3.2, DSS-AHC critical interval MAGE superfamily 6, DAM6, MAGE XP-2 antigen, MAGE-B2 antigenMAGEB2 (MAGE Family Member B2) is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68 % sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of MAGEB2 family enables the same function to be expressed under different transcriptional controls. MAGEB2 is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21.

Molecular Weight: 35kD

Gene ID: 4113

UniProt: O15479