Melatonin Receptor 1A antibody (AA 160-240)

Catalog No. ABIN7222560

The Rabbit Polyclonal anti-Melatonin Receptor 1A antibody is suitable to detect Melatonin Receptor 1A in samples from Human, Mouse and Rat. It has been validated for WB, IHC and ELISA.

Quick Overview for Melatonin Receptor 1A antibody (AA 160-240) (ABIN7222560)

Target: Melatonin Receptor 1A (MTNR1A)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Melatonin Receptor 1A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Melatonin Receptor 1A Antibody

Binding Specificity: AA 160-240

Purpose: Rabbit Anti-MEL-1A-R Polyclonal Antibody

Specificity: MEL-1A-R Polyclonal Antibody detects endogenous levels of MEL-1A-R protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human MEL-1A-R at AA range: 160-240

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Melatonin Receptor 1A

Target: Melatonin Receptor 1A (MTNR1A)

Alternative Name: MEL-1A-R

Background: MTNR1A, Melatonin receptor type 1A, Mel-1A-R, Mel1a receptorMTNR1A encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.

Gene ID: 4543

UniProt: P48039