Melatonin Receptor 1B antibody (AA 270-350)
Quick Overview for Melatonin Receptor 1B antibody (AA 270-350) (ABIN7215734)
Target
See all Melatonin Receptor 1B (MTNR1B) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 270-350
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Purpose
- MEL-1B-R Polyclonal Antibody
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Specificity
- MEL-1B-R Polyclonal Antibody detects endogenous levels of MEL-1B-R protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the C-terminal region of human MEL-1B-R at AA range: 270-350
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Melatonin Receptor 1B (MTNR1B)
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Alternative Name
- MEL-1B-R
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Background
- Rabbit Anti-MEL-1B-R Polyclonal Antibody,MTNR1B, Melatonin receptor type 1B, Mel-1B-R, Mel1b receptor,MTNR1B encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. Melatonin receptor type 1B is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin.,Melatonin receptor type 1B
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Molecular Weight
- observerd band 40kDa
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Gene ID
- 4544
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UniProt
- P49286
Target
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