MARCH6 antibody

Catalog No. ABIN7229570

The Rabbit Polyclonal anti-MARCH6 antibody is suitable to detect MARCH6 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for MARCH6 antibody (ABIN7229570)

Target: MARCH6 (Membrane-Associated Ring Finger (C3HC4) 6, E3 Ubiquitin Protein Ligase (MARCH6))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARCH6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MARCH6 Antibody

Purpose: Rabbit Anti-MARH6 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MARH6 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MARH6 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MARCH6

Target: MARCH6 (Membrane-Associated Ring Finger (C3HC4) 6, E3 Ubiquitin Protein Ligase (MARCH6))

Alternative Name: MARH6

Background: E3 ubiquitin-protein ligase MARCH6, Doa10 homolog, Membrane-associated RING finger protein 6, Membrane-associated RING-CH protein VI, MARCH-VI, Protein TEB-4, RING finger protein 176, RING-type E3 ubiquitin transferase MARCH6MARCH6 encodes a member of a family of membrane-associated E3 ubiquitin ligases containing RING-CH-type zinc finger motifs. Ubiquitination of type II deiodinase by the encoded protein is an important regulatory step in thyroid hormone signalling. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. MARCH6 (Membrane Associated Ring-CH-Type Finger 6) is a Protein Coding gene. Diseases associated with MARCH6 include Intrahepatic Cholestasis. Among its related pathways are Protein processing in endoplasmic reticulum and Transport to the Golgi and subsequent modification.

Molecular Weight: 100kD

Gene ID: 10299

UniProt: O60337