MGST1 antibody (AA 30-110)

Catalog No. ABIN7222464

This Rabbit Polyclonal antibody specifically detects MGST1 in WB and IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for MGST1 antibody (AA 30-110) (ABIN7222464)

Target: MGST1 (Microsomal Glutathione S-Transferase 1 (MGST1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MGST1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MGST1 Antibody

Binding Specificity: AA 30-110

Purpose: Rabbit Anti-MGST1 Polyclonal Antibody

Specificity: MGST1 Polyclonal Antibody detects endogenous levels of MGST1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human MGST1 at AA range: 30-110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MGST1

Target: MGST1 (Microsomal Glutathione S-Transferase 1 (MGST1))

Alternative Name: MGST1

Background: MGST1, GST12, MGST, Microsomal glutathione S-transferase 1, Microsomal GST-1, Microsomal GST-IThe MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. MGST1 encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress. Several transcript variants, some non-protein coding and some protein coding, have been found for this gene.

Molecular Weight: 18kD

Gene ID: 4257

UniProt: P10620