MRPL17 antibody (AA 100-180)

Catalog No. ABIN7224198

The Rabbit Polyclonal anti-MRPL17 antibody is suitable to detect MRPL17 in samples from Human, Mouse and Rat. It has been validated for IHC, ELISA and IF.

Quick Overview for MRPL17 antibody (AA 100-180) (ABIN7224198)

Target: MRPL17 (Mitochondrial Ribosomal Protein L17 (MRPL17))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL17 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-MRPL17 Antibody

Binding Specificity: AA 100-180

Purpose: Rabbit Anti-MRP-L17 Polyclonal Antibody

Specificity: MRP-L17 Polyclonal Antibody detects endogenous levels of MRP-L17 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human MRP-L17 at AA range: 100-180

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MRPL17

Target: MRPL17 (Mitochondrial Ribosomal Protein L17 (MRPL17))

Alternative Name: MRP-L17

Background: MRPL17, LIP2, 39S ribosomal protein L17, mitochondrial, L17mt, MRP-L17, LYST-interacting protein 2Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPL17 (mitochondrial ribosomal protein L17) encodes a 39S subunit protein.

Molecular Weight: 20kD

Gene ID: 63875

UniProt: Q9NRX2