MRPL19 antibody (AA 160-240)

Catalog No. ABIN7231086

This Rabbit Polyclonal antibody specifically detects MRPL19 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for MRPL19 antibody (AA 160-240) (ABIN7231086)

Target: MRPL19 (Mitochondrial Ribosomal Protein L19 (MRPL19))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL19 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MRPL19 Antibody

Binding Specificity: AA 160-240

Purpose: Rabbit Anti-RM19 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RM19 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RM19 protein at AA range: 160-240

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MRPL19

Target: MRPL19 (Mitochondrial Ribosomal Protein L19 (MRPL19))

Alternative Name: RM19

Background: 39S ribosomal protein L19, mitochondrial, L19mt, MRP-L19, 39S ribosomal protein L15, mitochondrial, L15mt, MRP-L15, Mitochondrial large ribosomal subunit protein bL19 mMRPL19 (Mitochondrial Ribosomal Protein L19) is a Protein Coding gene. Diseases associated with MRPL19 include Reading Disorder. Among its related pathways are Mitochondrial translation and Organelle biogenesis and maintenance. Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPL19 encodes a 39S subunit protein.

Molecular Weight: 32kD

Gene ID: 9801

UniProt: P49406