MRPL42 antibody (AA 50-130)

Catalog No. ABIN7221314

The Rabbit Polyclonal anti-MRPL42 antibody (ABIN7221314) specifically detects MRPL42 in ELISA, IHC and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for MRPL42 antibody (AA 50-130) (ABIN7221314)

Target: MRPL42 (Mitochondrial Ribosomal Protein L42 (MRPL42))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL42 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MRPL42 Antibody

Binding Specificity: AA 50-130

Purpose: Rabbit Anti-MRP-S32 Polyclonal Antibody

Specificity: MRP-S32 Polyclonal Antibody detects endogenous levels of MRP-S32 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human MRP-S32 at AA range: 50-130

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MRPL42

Target: MRPL42 (Mitochondrial Ribosomal Protein L42 (MRPL42))

Alternative Name: MRP-S32

Background: MRPL42, MRPL31, MRPS32, RPML31, HSPC204, PTD007, 39S ribosomal protein L42, mitochondrial, L42mt, MRP-L42, 28S ribosomal protein S32, mitochondrial, MRP-S32, S32mt, 39S ribosomal protein L31, mitochondrial, L31mt, MRP-L31Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPL42 encodes mitochondrial ribosomal protein L42 identified as belonging to both the 28S and the 39S subunits. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 4q, 6p, 6q, 7p, and 15q.

Gene ID: 28977

UniProt: Q9Y6G3