MRPL49 antibody (AA 10-90)

Catalog No. ABIN7224870

The Rabbit Polyclonal anti-MRPL49 antibody (ABIN7224870) specifically detects MRPL49 in ELISA, WB, IHC and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for MRPL49 antibody (AA 10-90) (ABIN7224870)

Target: MRPL49 (Mitochondrial Ribosomal Protein L49 (MRPL49))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL49 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MRPL49 Antibody

Binding Specificity: AA 10-90

Purpose: Rabbit Anti-MRP-L49 Polyclonal Antibody

Specificity: MRP-L49 Polyclonal Antibody detects endogenous levels of MRP-L49 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human MRP-L49 at AA range: 10-90

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MRPL49

Target: MRPL49 (Mitochondrial Ribosomal Protein L49 (MRPL49))

Alternative Name: MRP-L49

Background: MRPL49, C11orf4, NOF1, OK/SW-cl.67, 39S ribosomal protein L49, mitochondrial, L49mt, MRP-L49, Neighbor of FAU, NOF, Protein NOF1Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. Pseudogenes corresponding to MRPL49 (mitochondrial ribosomal protein L49)are found on chromosomes 5q and 8p.

Molecular Weight: 19kD

Gene ID: 740

UniProt: Q13405