The Rabbit Polyclonal anti-MRPL51 antibody is suitable to detect MRPL51 in samples from Human and Mouse. It has been validated for ELISA, WB, IHC and IF.
MRPL51
Reactivity: Human
ELISA
Host: Rabbit
Polyclonal
HRP
Application Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Expiry Date
12 months
Target
MRPL51
(Mitochondrial Ribosomal Protein L51 (MRPL51))
Alternative Name
MRP-L51
Background
MRPL51, MRP64, CDA09, HSPC241, 39S ribosomal protein L51, mitochondrial, L51mt, MRP-L51, bMRP-64, bMRP64Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPL51 (mitochondrial ribosomal protein L51) encodes a 39S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 4p and 21q.