MRPS18C antibody (AA 40-120)

Catalog No. ABIN7222964

This Rabbit Polyclonal antibody specifically detects MRPS18C in ELISA, WB, IHC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for MRPS18C antibody (AA 40-120) (ABIN7222964)

Target: MRPS18C (Mitochondrial Ribosomal Protein S18C (MRPS18C))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPS18C antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MRPS18C Antibody

Binding Specificity: AA 40-120

Purpose: Rabbit Anti-MRP-S18C Polyclonal Antibody

Specificity: MRP-S18C Polyclonal Antibody detects endogenous levels of MRP-S18C protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human MRP-S18C at AA range: 40-120

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MRPS18C

Target: MRPS18C (Mitochondrial Ribosomal Protein S18C (MRPS18C))

Alternative Name: MRP-S18C

Background: MRPS18C, CGI-134, 28S ribosomal protein S18c, mitochondrial, MRP-S18-c, Mrps18-c, S18mt-c, 28S ribosomal protein S18-1, mitochondrial, MRP-S18-1Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPS18C encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein mitochondrial ribosomal protein S18C is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 8p, 12p, 15q, and 22q.

Molecular Weight: 16kD

Gene ID: 51023

UniProt: Q9Y3D5