MTIF2 antibody (AA 450-530)

Catalog No. ABIN7229022

The Rabbit Polyclonal anti-MTIF2 antibody is suitable to detect MTIF2 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for MTIF2 antibody (AA 450-530) (ABIN7229022)

Target: MTIF2 (Mitochondrial Translational Initiation Factor 2 (MTIF2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTIF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MTIF2 Antibody

Binding Specificity: AA 450-530

Purpose: Rabbit Anti-IF2M Polyclonal Antibody

Specificity: The antibody detects endogenous levels of IF2M protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human IF2M protein at AA range: 450-530

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MTIF2

Target: MTIF2 (Mitochondrial Translational Initiation Factor 2 (MTIF2))

Alternative Name: IF2M

Background: Translation initiation factor IF-2, mitochondrial, IF-2MtMTIF2 (Mitochondrial Translational Initiation Factor 2) is a Protein Coding gene. Among its related pathways are Mitochondrial translation and Organelle biogenesis and maintenance. During the initiation of protein biosynthesis, initiation factor-2 (IF-2) promotes the binding of the initiator tRNA to the small subunit of the ribosome in a GTP-dependent manner. Prokaryotic IF-2 is a single polypeptide, while eukaryotic cytoplasmic IF-2 (eIF-2) is a trimeric protein. Bovine liver mitochondria contain IF-2(mt), an 85-kD monomeric protein that is equivalent to prokaryotic IF-2. The predicted 727-amino acid human protein contains a 29-amino acid presequence. Human IF-2(mt) shares 32 to 38 % amino acid sequence identity with yeast IF-2(mt) and several prokaryotic IF-2s, with the greatest degree of conservation in the G domains of the proteins.

Molecular Weight: 79kD

Gene ID: 4528

UniProt: P46199

Pathways: Ribonucleoprotein Complex Subunit Organization