MT-ND1 antibody (AA 150-230)

Catalog No. ABIN7215974

The Rabbit Polyclonal anti-MT-ND1 antibody (ABIN7215974) specifically detects MT-ND1 in WB, IHC, ELISA and IF. The antibody is reactive with Human and Rat samples.

Quick Overview for MT-ND1 antibody (AA 150-230) (ABIN7215974)

Target: MT-ND1 (Mitochondrially Encoded NADH Dehydrogenase 1 (MT-ND1))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MT-ND1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-MT-ND1 Antibody

Binding Specificity: AA 150-230

Purpose: Rabbit Anti-ND1 Polyclonal Antibody

Specificity: ND1 Polyclonal Antibody detects endogenous levels of ND1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human ND1 at AA range: 150-230

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MT-ND1

Target: MT-ND1 (Mitochondrially Encoded NADH Dehydrogenase 1 (MT-ND1))

Alternative Name: ND1

Background: MT-ND1, MTND1, NADH1, ND1, NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1MT-ND1 is a Protein Coding gene. Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Diseases associated with MT-ND1 include melas syndrome and leber hereditary optic neuropathy. Among its related pathways are Metabolism and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Gene Ontology (GO) annotations related to this gene include NADH dehydrogenase (ubiquinone) activity.

Molecular Weight: 36kD

Gene ID: 4535

UniProt: P03886