MSX1 antibody (AA 70-150)

Catalog No. ABIN7229772

The Rabbit Polyclonal anti-MSX1 antibody is suitable to detect MSX1 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for MSX1 antibody (AA 70-150) (ABIN7229772)

Target: MSX1 (Msh Homeobox 1 (MSX1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MSX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MSX1 Antibody

Binding Specificity: AA 70-150

Purpose: Rabbit Anti-MSX1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MSX1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MSX1 protein at AA range: 70-150

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MSX1

Target: MSX1 (Msh Homeobox 1 (MSX1))

Alternative Name: MSX1

Background: Homeobox protein MSX-1, Homeobox protein Hox-7, Msh homeobox 1-like proteinMSX1 encodes a member of the muscle segment homeobox gene family. The encoded protein functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins. It may also have roles in limb-pattern formation, craniofacial development, particularly odontogenesis, and tumor growth inhibition. Mutations in MSX1, which was once known as homeobox 7, have been associated with nonsyndromic cleft lip with or without cleft palate 5, Witkop syndrome, Wolf-Hirschom syndrome, and autosomoal dominant hypodontia.

Molecular Weight: 32kD

Gene ID: 4487

UniProt: P28360

Pathways: Regulation of Muscle Cell Differentiation, Positive Regulation of Response to DNA Damage Stimulus