MUC4 antibody (AA 1970-2050)

Catalog No. ABIN7229790

This Rabbit Polyclonal antibody specifically detects MUC4 in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for MUC4 antibody (AA 1970-2050) (ABIN7229790)

Target: MUC4 (Mucin 4, Cell Surface Associated (MUC4))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MUC4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MUC4 Antibody

Binding Specificity: AA 1970-2050

Purpose: Rabbit Anti-MUC4 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MUC4 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MUC4 protein at AA range: 1970-2050

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MUC4

Target: MUC4 (Mucin 4, Cell Surface Associated (MUC4))

Alternative Name: MUC4

Background: Mucin-4, MUC-4, Ascites sialoglycoprotein, ASGP, Pancreatic adenocarcinoma mucin, Testis mucin, Tracheobronchial mucinMUC4 (Mucin 4, Cell Surface Associated) is a Protein Coding gene. Among its related pathways are O-linked glycosylation and HIV Life Cycle. The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. MUC4 encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. At least two dozen transcript variants of MUC4 have been found, although for many of them the full-length transcript has not been determined or they are found only in tumor tissues. MUC4 contains a region in the coding sequence which has a variable number (>100) of 48 nt tandem repeats.

Molecular Weight: 238kD

Gene ID: 4585

UniProt: Q99102

Pathways: Regulation of Leukocyte Mediated Immunity