MAG antibody (C-Term)

Catalog No. ABIN7218548

The Rabbit Polyclonal anti-MAG antibody is suitable to detect MAG in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for MAG antibody (C-Term) (ABIN7218548)

Target: MAG (Myelin Associated Glycoprotein (MAG))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAG antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MAG Antibody

Binding Specificity: C-Term

Purpose: Rabbit Anti-MAG Polyclonal Antibody

Specificity: MAG Polyclonal Antibody detects endogenous levels of MAG protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human MAG

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MAG

Target: MAG (Myelin Associated Glycoprotein (MAG))

Alternative Name: MAG

Background: MAG, GMA, Myelin-associated glycoprotein, Siglec-4aMyelin-associated glycoprotein encoded by MAG is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.

Molecular Weight: 70kD

Gene ID: 4099

UniProt: P20916

Pathways: Neurotrophin Signaling Pathway