MYEF2 antibody (pThr312)

Catalog No. ABIN7222422

This Rabbit Polyclonal antibody specifically detects MYEF2 in ELISA, WB, IHC, IF and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for MYEF2 antibody (pThr312) (ABIN7222422)

Target: MYEF2 (Myelin Expression Factor 2 (MYEF2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYEF2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-MYEF2 Antibody

Binding Specificity: pThr312

Purpose: Rabbit Anti-MEF-2 (phospho Thr312) Polyclonal Antibody

Specificity: Phospho-MEF-2 (T312) Polyclonal Antibody detects endogenous levels of MEF-2 protein only when phosphorylated at T312.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human MEF-2 Phospho-Thr312

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IP 2-5 μg:mg lysate,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MYEF2

Target: MYEF2 (Myelin Expression Factor 2 (MYEF2))

Alternative Name: MEF-2

Background: MEF2A, MEF2, Myocyte-specific enhancer factor 2A, Serum response factor-like protein 1The protein encoded by MEF2A is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene.

Gene ID: 4205

UniProt: Q02078