MDFIC antibody (AA 100-180)

Catalog No. ABIN7229610

This Rabbit Polyclonal antibody specifically detects MDFIC in ELISA and WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for MDFIC antibody (AA 100-180) (ABIN7229610)

Target: MDFIC (MyoD Family Inhibitor Domain Containing (MDFIC))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MDFIC antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-MDFIC Antibody

Binding Specificity: AA 100-180

Purpose: Rabbit Anti-MDFIC Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MDFIC protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MDFIC protein at AA range: 100-180

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MDFIC

Target: MDFIC (MyoD Family Inhibitor Domain Containing (MDFIC))

Alternative Name: MDFIC

Background: MyoD family inhibitor domain-containing protein, I-mfa domain-containing protein, hICMDFIC (MyoD Family Inhibitor Domain Containing) is a Protein Coding gene. Diseases associated with MDFIC include T-Cell Leukemia and Hiv-1. Among its related pathways are Regulation of Wnt-mediated beta catenin signaling and target gene transcription. MDFIC product is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization, p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus. Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain.

Molecular Weight: 27kD

Gene ID: 29969

UniProt: Q9P1T7