Myosin XVIIIA antibody (AA 1920-2000)

Catalog No. ABIN7229808

The Rabbit Polyclonal anti-Myosin XVIIIA antibody (ABIN7229808) specifically detects Myosin XVIIIA in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for Myosin XVIIIA antibody (AA 1920-2000) (ABIN7229808)

Target: Myosin XVIIIA (MYO18A)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myosin XVIIIA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Myosin XVIIIA Antibody

Binding Specificity: AA 1920-2000

Purpose: Rabbit Anti-MY18A Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MY18A protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MY18A protein at AA range: 1920-2000

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Myosin XVIIIA

Target: Myosin XVIIIA (MYO18A)

Alternative Name: MY18A

Background: Unconventional myosin-XVIIIa, Molecule associated with JAK3 N-terminus, MAJN, Myosin containing a PDZ domain, Surfactant protein receptor SP-R210, SP-R210MYO18A (Myosin XVIIIA) is a Protein Coding gene. Diseases associated with MYO18A include 8P11 Myeloproliferative Syndrome. Among its related pathways are HIV Life Cycle and FGFR1 mutant receptor activation. The protein encoded by MYO18A can bind GOLPH3, linking the Golgi to the cytoskeleton and influencing Golgi membrane trafficking. The encoded protein is also part of a complex that assembles lamellar actomyosin bundles and may be required for cell migration.

Molecular Weight: 225kD

Gene ID: 399687

UniProt: Q92614