MTPN antibody

Catalog No. ABIN7229782

The Rabbit Polyclonal anti-MTPN antibody is suitable to detect MTPN in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for MTPN antibody (ABIN7229782)

Target: MTPN (Myotrophin (MTPN))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTPN antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MTPN Antibody

Purpose: Rabbit Anti-MTPN Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MTPN protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MTPN protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MTPN

Target: MTPN (Myotrophin (MTPN))

Alternative Name: MTPN

Background: Myotrophin, Protein V-1The transcript produced from MTPN gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3' end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen that is associated with myeloproliferative disease.

Molecular Weight: 12kD

Gene ID: 136319

UniProt: P58546