MYOZ2 antibody (AA 21-70)

Catalog No. ABIN7226966

This Rabbit Polyclonal antibody specifically detects MYOZ2 in WB, ELISA and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for MYOZ2 antibody (AA 21-70) (ABIN7226966)

Target: MYOZ2 (Myozenin 2 (MYOZ2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYOZ2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-MYOZ2 Antibody

Binding Specificity: AA 21-70

Purpose: Rabbit Anti-MYOZ2 Polyclonal Antibody

Specificity: The antibody detects endogenous MYOZ2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthetic peptide from human protein at AA range: 21-70

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MYOZ2

Target: MYOZ2 (Myozenin 2 (MYOZ2))

Alternative Name: MYOZ2

Background: MYOZ2, C4orf5The protein encoded by MYOZ2 (myozenin 2) belongs to a family of sarcomeric proteins that bind to calcineurin, a phosphatase involved in calcium-dependent signal transduction in diverse cell types. These family members tether calcineurin to alpha-actinin at the z-line of the sarcomere of cardiac and skeletal muscle cells, and thus they are important for calcineurin signaling. Mutations in MYOZ2 cause cardiomyopathy familial hypertrophic type 16, a hereditary heart disorder.

Molecular Weight: 30kD

Gene ID: 51778

UniProt: Q9NPC6