NACAD antibody (AA 350-430)
Quick Overview for NACAD antibody (AA 350-430) (ABIN7220650)
Target
See all NACAD AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 350-430
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Purpose
- NACAD Polyclonal Antibody
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Specificity
- NACAD Polyclonal Antibody detects endogenous levels of NACAD protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the Internal region of human NACAD at AA range: 350-430
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- NACAD (NAC alpha Domain Containing (NACAD))
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Alternative Name
- NACAD
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Background
- Rabbit Anti-NACAD Polyclonal Antibody,NACAD, KIAA0363, NAC-alpha domain-containing protein 1,May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). May bind to nascent polypeptide chains as they emerge from the ribosome and block their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites).,NAC-alpha domain-containing protein 1
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Molecular Weight
- observerd band 140kDa
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Gene ID
- 23148
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UniProt
- O15069
Target
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